Relationships between 2H4 (CD45RA) and UCHL1 (CD45RO) expression by normal blood CD4+CD8−, CD4−CD8+, CD4−CD8dim+, CD3+ CD4−CD8− and CD3−CD4−CD8− lymphocytes

Relationship between Virus Infections and the number of Extrathymic Activated CD4CD8 T Cells

Interleukin 2 induces the expression of CD45RO and the memory phenotype by CD45RA+ peripheral blood lymphocytes

The CD45RA and CD45RO isoforms of the leukocyte common antigen identify functionally distinct "naive" and "memory" T cell subsets. While antigenic and mitogenic stimuli are known to initiate transition from the naive to memory state, little is known about the role of cytokines in this process. This report demonstrates that in vitro exposure of purified CD45RA+/CD45RO- peripheral blood lymphocyt...

ATM Deficiency Disrupts TCRα Locus Integrity and the Maturation of CD4CD8 Thymocytes

Author contributions: I.M performed most of the research, analyzed data and co-wrote the paper. R.A.G performed some experiments and analyzed data. L.N contributed to the design of the study and supervised experimental work. A.C designed and performed the statistical analysis of the cytogenetics data. C.J.G and J.S.D designed the study, supervised the experimental work and co-wrote the manuscript.

Signal-Regulated Kinase Activation in CD4CD8 Thymocytes and Supports Their Differentiation to the CD4 Lineage

Nuclear Factor kB Is Required for Peptide Antigen-Induced Differentiation of a CD4CD8 Thymocyte Line